Back to Search
Start Over
Variable habitat conditions drive species covariation in the human microbiota.
- Source :
- PLoS Computational Biology; 4/27/2017, Vol. 13 Issue 4, p1-18, 18p
- Publication Year :
- 2017
-
Abstract
- Two species with similar resource requirements respond in a characteristic way to variations in their habitat—their abundances rise and fall in concert. We use this idea to learn how bacterial populations in the microbiota respond to habitat conditions that vary from person-to-person across the human population. Our mathematical framework shows that habitat fluctuations are sufficient for explaining intra-bodysite correlations in relative species abundances from the Human Microbiome Project. We explicitly show that the relative abundances of closely related species are positively correlated and can be predicted from taxonomic relationships. We identify a small set of functional pathways related to metabolism and maintenance of the cell wall that form the basis of a common resource sharing niche space of the human microbiota. [ABSTRACT FROM AUTHOR]
- Subjects :
- HUMAN microbiota
HABITATS
MICROORGANISMS
METABOLISM
POPULATION
BACTERIAL population
Subjects
Details
- Language :
- English
- ISSN :
- 1553734X
- Volume :
- 13
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- PLoS Computational Biology
- Publication Type :
- Academic Journal
- Accession number :
- 122724311
- Full Text :
- https://doi.org/10.1371/journal.pcbi.1005435