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Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis.
- Source :
- Science Translational Medicine; 5/13/2015, Vol. 7 Issue 287, p1-10, 10p, 4 Color Photographs
- Publication Year :
- 2015
-
Abstract
- The article focuses findings of a study on role of functional inflammatory profiles in distinguishing myelin-reactive T cells from patients with multiple sclerosis. It states that libraries derived from the CCR6+ T cells from patients with MS exhibited significantly enhanced production of interferon gamma, and mentions that transcriptomes of myelin-specific CCR6+ T cells from patients with MS were distinct. It infers that myelin-reactive T cells may act to limit disease progression.
Details
- Language :
- English
- ISSN :
- 19466234
- Volume :
- 7
- Issue :
- 287
- Database :
- Complementary Index
- Journal :
- Science Translational Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 122648485
- Full Text :
- https://doi.org/10.1126/scitranslmed.aaa8038