Early infancy microbial and metabolic alterations affect risk of childhood asthma.

Authors :: Arrieta, Marie-Claire
Stiemsma, Leah T.
Dimitriu, Pedro A.
Thorson, Lisa
Russell, Shannon
Yurist-Doutsch, Sophie
Kuzeljevic, Boris
Gold, Matthew J.
Britton, Heidi M.
Lefebvre, Diana L.
Subbarao, Padmaja
Mandhane, Piush
Becker, Allan
McNagny, Kelly M.
Sears, Malcolm R.
Kollmann, Tobias
Mohn, William W.
Turvey, Stuart E.
Finlay, B. Brett
Source :: Science Translational Medicine; 9/30/2015, Vol. 7 Issue 307, p1-14, 14p, 1 Diagram, 4 Graphs
Publication Year :: 2015
Abstract: The article offers insight to Canadian Healthy Infant Longitudinal Development Study focusing on the impact of early infancy microbial and metabolic alterations on the risk of childhood asthma. Topics discussed include link between gut microbial dysbiosis; microbe-derived functional changes in infants; and the role of Faecalibacterium, Lachnospira, Veillonella-mediated amelioration of murine lung inflammation.

Subjects :: ASTHMA in children
GUT microbiome
VEILLONELLA
LUNGS
INFANT health

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