Back to Search Start Over

Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults.

Authors :
Ogwang, Caroline
Kimani, Domtila
Edwards, Nick J.
Roberts, Rachel
Mwacharo, Jedidah
Bowyer, Georgina
Bliss, Carly
Hodgson, Susanne H.
Njuguna, Patricia
Viebig, Nicola K.
Nicosia, Alfredo
Gitau, Evelyn
Douglas, Sandy
Illingworth, Joe
Marsh, Kevin
Lawrie, Alison
Imoukhuede, Egeruan B.
Ewer, Katie
Urban, Britta C.
Hill, Adrian V. S.
Source :
Science Translational Medicine; 5/6/2015, Vol. 7 Issue 286, p1-8, 8p, 3 Charts, 3 Graphs
Publication Year :
2015

Abstract

The article looks at a study regarding vaccination with the recombinant viral vectors chimpanzee adenovirus 63 and modified vaccinia Ankara encoding the malaria peptide sequence multiple epitope string and thrombospondin-related adhesion protein (ME-TRAP). It mentions antimalarials to clear parasitemia and conducted polymerase chain reaction (PCR) with the malaria parasite Plasmodium falciparum. It also mentions vaccination reduced the risk of infection.

Details

Language :
English
ISSN :
19466234
Volume :
7
Issue :
286
Database :
Complementary Index
Journal :
Science Translational Medicine
Publication Type :
Academic Journal
Accession number :
122643697
Full Text :
https://doi.org/10.1126/scitranslmed.aaa2373