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Metabolism and health effects of phyto-estrogens.
- Source :
- Critical Reviews in Food Science & Nutrition; 2017, Vol. 57 Issue 11, p2432-2454, 23p
- Publication Year :
- 2017
-
Abstract
- Phyto-estrogens are plant-derived compounds that can exert various estrogenic and anti-estrogenic effects, and are usually used as a natural alternative to estrogen replacement due to their health benefits, including a lowered risk of osteoporosis, heart disease, breast cancer, and menopausal symptoms. Phyto-estrogens are also considered as endocrine disruptors due to their structure similar to human female hormone 17-β oestradiol. However, the issue of whether phyto-estrogens are beneficial or harmful to human health remains unknown, as this may depend on the dose, form, level and duration of administration of phyto-estrogens, and influence by genetics, metabolism, gut physiology, age, diet, and the health status of individuals. Clarification on this issue is necessary for the sake of their two-side effects on human health and rapidly increasing global consumption of phyto-estrogens. This review mainly includes the metabolism of phyto-estrogens and weighs the evidence for and against the purported health benefits and adverse effects of phyto-estrogens. [ABSTRACT FROM PUBLISHER]
- Subjects :
- METABOLISM
ESTROGEN
ESTRADIOL
BIOCHEMISTRY
SEX hormones
Subjects
Details
- Language :
- English
- ISSN :
- 10408398
- Volume :
- 57
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- Critical Reviews in Food Science & Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 122541251
- Full Text :
- https://doi.org/10.1080/10408398.2015.1077194