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Reaction of phosphofructokinase 2/fructose 2,6-bisphosphatase with monoclonal antibodies.

Authors :
van Schaftingen, Emile
Coulie, Pierre G.
van Snick, Jacques
Hers, Henri-Gery
Source :
European Journal of Biochemistry; 9/1/86, Vol. 159 Issue 2, p367-373, 7p
Publication Year :
1986

Abstract

Reports on the reaction of monoclonal antibodies with phosphofructokinase 2/fructose 2,6-bisphosphatase. Derivation of monoclonal antibodies from immunized mice; Discovery of clones that secrete antibodies that react with immunabsorbent assay antigens; Use of subcloned clones for analyzing antibody reaction to bifunctional enzymes; Evidence of bifunctionality by the enzyme through the similar activities of the cloned antibodies.

Details

Language :
English
ISSN :
00142956
Volume :
159
Issue :
2
Database :
Complementary Index
Journal :
European Journal of Biochemistry
Publication Type :
Academic Journal
Accession number :
12242819
Full Text :
https://doi.org/10.1111/j.1432-1033.1986.tb09877.x