An Agaroid-Carrageenan Hybrid Type Backbone Structure for the Antithrombotic Sulfated Polysaccharide from Grateloupia indica Boergensen (Halymeniales, Rhodophyta).

Authors :: Sen Sr., A. K.
Das, A. K.
Sarkar, K. K.
Siddhanta, A. K.
Takano, R.
Kamei, K.
Hara, S.
Source :: Botanica Marina; 2002, Vol. 45 Issue 4, p331-338, 8p
Publication Year :: 2002
Abstract: The water-soluble antithrombotic polysaccharide sulfate fraction designated GI-1 was isolated from the marine red alga Grateloupia indica. It consists mainly of <subscript>D</subscript>-galactose (Gal), <subscript>L</subscript>-Gal, 3,6-anhydro-<subscript>D</subscript>-galactose (<subscript>D</subscript>-AnGal) and 3,6-anhydro <subscript>L</subscript>-galactose (<subscript>L</subscript>-AnGal). On the basis of the results from <subscript>13</subscript>C NMR and methylation analysis of completely desulfated GI-1, we assigned a typical agarocolloid-carrageenan hybrid type of the backbone consisting of both disaccharide repeating units, [→3)β-<subscript>D</subscript>-Gal(1→4)α-<subscript>D</subscript>-Gal(1→] and [→3)β-<subscript>D</subscript>-Gal(1→4)-<subscript>L</subscript>-Gal(1→]. In addition, two repeating units, [→3)β-<subscript>D</subscript>-Gal(1→4)α-<subscript>D</subscript>-AnGal(1→] and [→3)β-<subscript>D</subscript>-Gal(1→4)α-<subscript>L</subscript>-An-Gal(1→],were also suggested for the native GI-1 from partial methanolysis and <superscript>13</superscript>C NMR studies. [ABSTRACT FROM AUTHOR]

Subjects :: RED algae
GALACTOSE
GLYCOSIDES
MARINE biology
AQUATIC biology
ECOLOGY

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