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Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence.
- Source :
- Science Translational Medicine; 4/13/2016, Vol. 8 Issue 334, p1-11, 11p, 5 Color Photographs, 2 Charts
- Publication Year :
- 2016
-
Abstract
- The article presents research demonstrating Janus kinase 2 (JAK2) gene dependence of triple-negative breast cancers with JAK2 amplification. Topics discussed include the identification of JAK2 amplifications in breast cancer, the attribution of phenotypes to a cell population, and the potential of JAK2 amplification as JAK2 dependence biomarker.
Details
- Language :
- English
- ISSN :
- 19466234
- Volume :
- 8
- Issue :
- 334
- Database :
- Complementary Index
- Journal :
- Science Translational Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 122228175
- Full Text :
- https://doi.org/10.1126/scitranslmed.aad3001