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Boronic acid-modified alginate enables direct formation of injectable, self-healing and multistimuli-responsive hydrogels.

Authors :
Pettignano, Asja
Grijalvo, Santiago
Häring, Marleen
Eritja, Ramon
Tanchoux, Nathalie
Quignard, Françoise
Díaz Díaz, David
Source :
Chemical Communications; 3/21/2017, Vol. 53 Issue 23, p3350-3353, 4p
Publication Year :
2017

Abstract

One-step functionalization of alginate with boronic acid groups allowed spontaneous formation of biocompatible hydrogels under basic conditions without additional complementary molecules or crosslinking agents. The dynamic nature of boronate ester bonds formed with vicinal diols present on alginate pyranose rings provided remarkable self-healing, injectable and multi-stimuli responsive properties to the material. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
BORONIC acids
ALGINATES
HYDROGELS

Details

Language :
English
ISSN :
13597345
Volume :
53
Issue :
23
Database :
Complementary Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
121889805
Full Text :
https://doi.org/10.1039/c7cc00765e