Prediction of infarct size using two-dimensional speckle tracking echocardiography in acute myocardial infarction.

Background This study aimed to determine the myocardial damage (infarct size provided by cardiac single-photon emission tomography) in early stages of the infarction using longitudinal strain and rotational parameters of the left ventricle. Methods The study included 66 patients with anterior myocardial infarction ( AMI) and 62 patients with inferior myocardial infarction ( IMI) who underwent primary percutaneous intervention as well as a control group consisting of 50 healthy subjects. LV rotational parameters based on parasternal short-axis views in basal and apical planes and global longitudinal strain were measured with apical four-chamber, apical two-chamber, and apical long-axis views. Results There was a significant positive correlation between infarct size and GLPSavg ( r=−.55 <.001), GTOR angle ( r=−.52, P<.001), apical rotation angle ( r=−.40 <.001, and EF ( r=−.43, <.001). While cutoff values were GLPSavg: 11.9 ( AUC=0.78), GTOR angle: 11.4° ( AUC=0.77), apical rotation angle: 7.1° ( AUC=0.76) for patients with an infarct size greater than 20%, the cutoff values were GLPSavg: 10.7 ( AUC=0.75), GTOR angle: 8.7° ( AUC=0.86), apical rotation angle: 4.35° ( AUC=0.87) for those with an infarct size greater than 40%. Conclusion GLPSavg, GTOR angle, and apical rotation angle values may be used to determine the extent of infarction in early post- MI period, thereby allowing precautions to be taken for remodeling in early stages. [ABSTRACT FROM AUTHOR]