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Reduction of hypoglycaemic events with a behavioural intervention: a randomized clinical trial for paediatric patients with Type 1 diabetes mellitus.
- Source :
- Diabetic Medicine; Mar2017, Vol. 34 Issue 3, p340-347, 8p
- Publication Year :
- 2017
-
Abstract
- Aims To determine if a low-intensity, clinic-integrated behavioural intervention reduced the incidence of hypoglycaemic events in children with Type 1 diabetes. Methods A total of 390 families with children with Type 1 diabetes were enrolled in a 2-year, randomized clinical trial of a behavioural intervention. The intervention was designed to improve diabetes management practices by targeting the family's diabetes problem-solving skills. Hypoglycaemic events were categorized in two groups: those treated by oral ingestion and those treated by parenteral therapy. Events were self-reported by participants at each clinic visit, which occurred approximately every 3-4 months. Analyses included two-sample t-tests, the mean cumulative function test, and the Cox proportional hazards model for recurrent events to compare the incidence between groups. Results Across the entire 2-year study period, the incidence of hypoglycaemic events treated by oral ingestion of glucose-rich foods and events requiring parenteral therapy did not significantly differ between study conditions; however, during the second year of participant enrolment, the incidence of events treated by oral ingestion in the intervention group was 13.6 per 100 person-years compared with 27.3 per 100 patient-years in the control group ( P = 0.02). The hazard ratio of these events during the second year was 0.49 (95% CI 0.27-0.90; P = 0.02). Conclusions Our findings suggest the need for a long-term (> 1 year) focus on the implementation of interventions targeting diabetes management in young people. Behavioural interventions targeting problem-solving skills could be considered as practical, non-pharmacological strategies to reduce hypoglycaemia in adolescents with Type 1 diabetes. [ABSTRACT FROM AUTHOR]
- Subjects :
- HYPOGLYCEMIA
TREATMENT of diabetes
TYPE 1 diabetes
BEHAVIOR therapy
BLOOD sugar
CONFIDENCE intervals
INGESTION
INSULIN
PARENTERAL feeding
PROBLEM solving
RESEARCH funding
SELF-evaluation
T-test (Statistics)
RANDOMIZED controlled trials
DISEASE incidence
PROPORTIONAL hazards models
DATA analysis software
PREVENTION
Subjects
Details
- Language :
- English
- ISSN :
- 07423071
- Volume :
- 34
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Diabetic Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 121236242
- Full Text :
- https://doi.org/10.1111/dme.12744