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The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice.

Authors :
Khayati, Khoosheh
Antikainen, Henri
Bonder, Edward M.
Weber, Gregory F.
Kruger, Warren D.
Jakubowski, Hieronim
Dobrowolski, Radek
Source :
FASEB Journal; Feb2017, Vol. 31 Issue 2, p598-609, 12p
Publication Year :
2017

Details

Language :
English
ISSN :
08926638
Volume :
31
Issue :
2
Database :
Complementary Index
Journal :
FASEB Journal
Publication Type :
Academic Journal
Accession number :
121142888
Full Text :
https://doi.org/10.1096/fj.201600915R