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Must research benefit human subjects if it is to be permissible?
- Source :
- Journal of Medical Ethics; Feb2017, Vol. 43 Issue 2, p114-117, 4p
- Publication Year :
- 2017
-
Abstract
- Must medical experiments with human subjects offer them a 'favourable risk-benefit ratio', that is, more expectation of benefit than harm or burden, if they are to be judged as ethically justified? Ethical justification is easier for experiments that do offer net benefit to subjects, but ethical justification is possible also for some experiments that do not. Basic science experiments with healthy volunteers and 'Phase I' drug trials that seek to determine tolerable dosage levels are routinely approved by ethical review committees; moreover, guidance they receive from government funding agencies specifically asks them to weigh risks to subjects against benefits to subjects and also benefits to those who may benefit from the knowledge gained in the experiment. If a puzzle remains, it is why there remains any assumption that research ethics requires a 'favourable risk-benefit ratio' for the individual research subject. [ABSTRACT FROM AUTHOR]
- Subjects :
- MEDICAL experimentation on humans
HIV infections
THERAPEUTICS
HIV-positive persons
CLINICAL trials
MEDICAL research
HEALTH
HIV prevention
INFORMED consent & ethics
MEDICAL research ethics
DISCLOSURE
HUMAN rights
RESEARCH funding
RISK assessment
INSTITUTIONAL review boards
SOCIAL responsibility
GOVERNMENT regulation
HUMAN research subjects
PHYSICIANS' oaths
DISEASE eradication
ETHICS
Subjects
Details
- Language :
- English
- ISSN :
- 03066800
- Volume :
- 43
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Journal of Medical Ethics
- Publication Type :
- Academic Journal
- Accession number :
- 120970768
- Full Text :
- https://doi.org/10.1136/medethics-2015-103123