Clinical trial among Scottish children of an anti-caries dentifrice containing 2% sodium monofluorophosphate.

A clinical trial was commenced in 1968 on the Island of Lewis, Scotland, to evaluate the effects of a new dentifrice formulation containing, as its main active ingredient, 2 % monofluorophosphate. The trial design conformed to international protocol and three age groups of children, namely, 5-year-olds, 8-year-olds and 11-year-olds, participated for a three-year period. The results show that the dentifrice is an effective anti-caries agent and the magnitude of its effects is generally greater than reported in studies of other dentifrice products. [ABSTRACT FROM AUTHOR]