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The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS brains.

Authors :
Conlon, Erin G.
Lei Lu
Sharma, Aarti
Takashi Yamazaki
Timothy Tang
Shneider, Neil A.
Manley, James L.
Source :
eLife; 2016, p1-28, 28p
Publication Year :
2016

Details

Language :
English
ISSN :
2050084X
Database :
Complementary Index
Journal :
eLife
Publication Type :
Academic Journal
Accession number :
120850093
Full Text :
https://doi.org/10.7554/eLife.17820