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The selective effect of plasma activated medium in an in vitro co-culture of liver cancer and normal cells.
- Source :
- Journal of Applied Physics; 2017, Vol. 121 Issue 1, p1-6, 6p, 1 Color Photograph, 1 Diagram, 1 Chart, 2 Graphs
- Publication Year :
- 2017
-
Abstract
- In this work, a co-culture system with liver cancer cell line HepG2 and normal cell line L02 is used to investigate the selective effect on cancer and normal cells by plasma activated medium (PAM), which is closer to the real environment where cancer cells develop. Besides, the co-culture system is a better model to study the selective effect than the widely used separate culture systems, where the cancer cell line and normal cell line are cultured independently. By using the co-culture system, it is found that there is an optimum dose of PAM to induce significant cancer cell apoptosis while keeping minimum damage to normal cells. [ABSTRACT FROM AUTHOR]
- Subjects :
- CANCER cell culture
CELL lines
PLASMA gases
APOPTOSIS
LIVER cancer
Subjects
Details
- Language :
- English
- ISSN :
- 00218979
- Volume :
- 121
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Journal of Applied Physics
- Publication Type :
- Academic Journal
- Accession number :
- 120587937
- Full Text :
- https://doi.org/10.1063/1.4973484