Primula dermatitis: more than one allergen?

Contact allergic reactions to Primula obconica have been detected for the past several years with a patch test to synthetic primin 0.01% pet. Since most such cases are clinically undetectable, primin has been included in the European standard series. Since February 1985, the authors have routinely tested primin 0.01% pet, in 4253 consecutive patients. It was positive 13 times, but the authors would have missed primula allergy in 2 patients if they had relied exclusively on primin. A 28-year-old woman had recurring outbreaks of itchy vesicles on the fingertips, from February to May 1988, which progressively worsened and extended to the palms and the backs of her hands.