Back to Search Start Over

Tau Structures.

Authors :
Avila, Jesus
Jiménez, Juan S.
Sayas, Carmen L.
Bolós, Marta
Zabala, Juan C.
Rivas, Germán
Hernández, Felix
Cheng-Xin Gong
Yingjun Zhao
Source :
Frontiers in Aging Neuroscience; 11/8/2016, Vol. 8, p1-10, 10p
Publication Year :
2016

Abstract

Tau is amicrotubule-associated protein that plays an important role in axonal stabilization, neuronal development, and neuronal polarity. In this review, we focus on the primary, secondary, tertiary, and quaternary tau structures. We describe the structure of tau from its specific residues until its conformation in dimers, oligomers, and larger polymers in physiological and pathological situations. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16634365
Volume :
8
Database :
Complementary Index
Journal :
Frontiers in Aging Neuroscience
Publication Type :
Academic Journal
Accession number :
119368459
Full Text :
https://doi.org/10.3389/fnagi.2016.00262