Hypercholesterolemia Associated with Subclinical Hypothyroidism in NCR Population.

Background: Subclinical hypothyroidism characterised by elevated level of total cholesterol, is controversial. Females are more affected by subclinical hypothyroidism comparing to males. Material & Methods: Total 131 both male & female were enrolled for the study compared with 61 healthy controls. Body mass index, serum concentration of TSH and FT₄ and Total cholesterol was measured. Thyroid profile of the participants was estimated by ELISA. Total cholesterol (TC) was measured by CHOD-POD method. Results: SCH patients were characterised by higher body mass index and elevated level of total cholesterol compared to control group (<0.01). Females with SCH were having higher BMI (<0.01) and higher total cholesterol (<0.05) when compared with male of SCH. TSH was positively correlated with TC in male group of SCH (r=0.32, p= <0.05) as well as female group of SCH(r=0.34, p=<0.05). Conclusion: Hypercholesterolemia was associated with subclinical hypothyroidism. Females with SCH were characterised by higher risk of hypercholesterolemia comparing to males. [ABSTRACT FROM AUTHOR]