Human gut-on-a-chip technology: will this revolutionize our understanding of IBD and future treatments?

The authors reflect on the use of human gut-on-a-chip technology to understand inflammatory bowel diseases (IBD), such as ulcerative colitis (UC) and Crohn's disease (CD), and treatments. Topics discussed include the limitations of existing IBD models, development of biomimetic human gut-on-a-chip microphysiological system, and innovations for clinical and pharmaceutical applications.