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Elevated Levels of Plasma Superoxide Dismutases 1 and 2 in Patients with Coronary Artery Disease.
- Source :
- BioMed Research International; 10/17/2016, Vol. 2016, p1-9, 9p
- Publication Year :
- 2016
-
Abstract
- Aims. To measure plasma levels of superoxide dismutases 1, 2, and 3 (SOD1, 2, 3) and determine whether SODs can function as biomarkers for coronary artery disease (CAD). Patients & Methods. Patient groups were as follows: patients with stable angina pectoris (SAP, n=33), patients with acute coronary syndrome (ACS, n=49), and controls (n=42). Protein quantification was done using ELISA. Results. The concentrations of plasma SOD1 and SOD2 were higher in CAD than in healthy controls. No difference in SOD3 levels between CAD and control groups was found. Limited correlations were found between SODs and gender, age, and severity of coronary artery stenosis. Conclusions. Plasma levels of SOD1 and SOD2 were elevated in patients with CAD and might serve as surrogate biomarkers for CAD. [ABSTRACT FROM AUTHOR]
- Subjects :
- ANGINA pectoris
BIOMARKERS
CORONARY artery stenosis
CORONARY disease
STATISTICAL correlation
ENZYME-linked immunosorbent assay
PROBABILITY theory
RESEARCH funding
SUPEROXIDE dismutase
SEVERITY of illness index
RECEIVER operating characteristic curves
DATA analysis software
DESCRIPTIVE statistics
CORONARY angiography
ONE-way analysis of variance
Subjects
Details
- Language :
- English
- ISSN :
- 23146133
- Volume :
- 2016
- Database :
- Complementary Index
- Journal :
- BioMed Research International
- Publication Type :
- Academic Journal
- Accession number :
- 118852741
- Full Text :
- https://doi.org/10.1155/2016/3708905