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Presenile diffuse familial sebaceous hyperplasia successfully treated with low-dose isotretinoin: A report of two cases and review of the published work.
- Source :
- Journal of Dermatology; Oct2016, Vol. 43 Issue 10, p1205-1208, 4p
- Publication Year :
- 2016
-
Abstract
- Presenile diffuse familial sebaceous hyperplasia ( PDFSH) presents as extensive yellowish papules with central umbilication on the face without involvement of periorificial regions and occurs in adolescents or young adults with a positive family history. Thirteen cases of PDFSH have been reported in the English-language published work, 10 of which responded to oral isotretinoin from 0.5 to 1 mg/kg per day but recurrences were often observed. Herein, we report two cases of PDFSH, which were successfully managed without recurrence with prolonged low-dose isotretinoin (0.2 mg/kg per day, a cumulative dose of 41 and 64 mg/kg, respectively). Treatment protocols among different published works were reviewed to verify the efficacy of isotretinoin. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03852407
- Volume :
- 43
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Journal of Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 118553422
- Full Text :
- https://doi.org/10.1111/1346-8138.13416