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The inhibition of cell proliferation and induction of apoptosis in pancreatic ductal adenocarcinoma cells by verrucarin A, a macrocyclic trichothecene, is associated with the inhibition of Akt/NF-κB/mTOR prosurvival signaling.

Authors :
DEEB, DORRAH
XIAOHUA GAO
YONGBO LIU
YIGUAN ZHANG
JIAJIU SHAW
VALERIOTE, FREDERICK A.
GAUTAM, SUBHASH C.
Source :
International Journal of Oncology; Sep2016, Vol. 49 Issue 3, p1139-1147, 9p
Publication Year :
2016

Details

Language :
English
ISSN :
10196439
Volume :
49
Issue :
3
Database :
Complementary Index
Journal :
International Journal of Oncology
Publication Type :
Academic Journal
Accession number :
117971423
Full Text :
https://doi.org/10.3892/ijo.2016.3587