Emerging therapies in large vessel vasculitis.

The author discusses development of research regarding therapies for treatment of large vessel vasculitis (LVV). Topics discussed include illustration of stages involved in disease progression, observation of high-dose glucocorticoids (GC) as mainstay in LVV treatment, utilization of Methotrexate as adjunctive therapy leads to reduction in GC exposure, involvement of Leflunomide as steroid-sparing for treatment of giant cell arteritis (GCA) and elucidation of Abatacept as anti-T cell therapy.