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Nurse-led group consultation intervention reduces depressive symptoms in men with localised prostate cancer: a cluster randomised controlled trial.
- Source :
- BMC Cancer; 8/16/2016, Vol. 16, p1-12, 12p, 1 Diagram, 4 Charts
- Publication Year :
- 2016
-
Abstract
- <bold>Background: </bold>Radiotherapy for localised prostate cancer has many known and distressing side effects. The efficacy of group interventions for reducing psychological morbidity is lacking. This study investigated the relative benefits of a group nurse-led intervention on psychological morbidity, unmet needs, treatment-related concerns and prostate cancer-specific quality of life in men receiving curative intent radiotherapy for prostate cancer.<bold>Methods: </bold>This phase III, two-arm cluster randomised controlled trial included 331 men (consent rate: 72 %; attrition: 5 %) randomised to the intervention (nā=ā166) or usual care (nā=ā165). The intervention comprised four group and one individual consultation all delivered by specialist uro-oncology nurses. Primary outcomes were anxious and depressive symptoms as assessed by the Hospital Anxiety and Depression Scale. Unmet needs were assessed with the Supportive Care Needs Survey-SF34 Revised, treatment-related concerns with the Cancer Treatment Scale and quality of life with the Expanded Prostate Cancer Index -26. Assessments occurred before, at the end of and 6 months post-radiotherapy. Primary outcome analysis was by intention-to-treat and performed by fitting a linear mixed model to each outcome separately using all observed data.<bold>Results: </bold>Mixed models analysis indicated that group consultations had a significant beneficial effect on one of two primary endpoints, depressive symptoms (p = 0.009), and one of twelve secondary endpoints, procedural concerns related to cancer treatment (p = 0.049). Group consultations did not have a significant beneficial effect on generalised anxiety, unmet needs and prostate cancer-specific quality of life.<bold>Conclusions: </bold>Compared with individual consultations offered as part of usual care, the intervention provides a means of delivering patient education and is associated with modest reductions in depressive symptoms and procedural concerns. Future work should seek to confirm the clinical feasibility and cost-effectiveness of group interventions.<bold>Trial Registration: </bold>Australian and New Zealand Clinical Trials Registry ANZCTRN012606000184572 . 1 March 2006. [ABSTRACT FROM AUTHOR]
- Subjects :
- NURSE-led clinics
CANCER radiotherapy
PROSTATE cancer patients
DRUG side effects
ANXIETY
QUALITY of life
ANXIETY treatment
THERAPEUTICS
MENTAL health
ADAPTABILITY (Personality)
COMPARATIVE studies
COUNSELING
MENTAL depression
FOCUS groups
RESEARCH methodology
MEDICAL cooperation
NURSES
PROSTATE tumors
PSYCHOLOGICAL tests
RESEARCH
OCCUPATIONAL roles
EVALUATION research
RANDOMIZED controlled trials
TREATMENT effectiveness
PSYCHOLOGY
Subjects
Details
- Language :
- English
- ISSN :
- 14712407
- Volume :
- 16
- Database :
- Complementary Index
- Journal :
- BMC Cancer
- Publication Type :
- Academic Journal
- Accession number :
- 117563551
- Full Text :
- https://doi.org/10.1186/s12885-016-2687-1