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Synthesis, crystal structure, Hirshfeld surface analysis and DNA binding properties of interactions with lattice pyrazinamide and its zinc(II) coordination polymer.

Authors :
Liu, Qing-Ling
Yang, Li-Jing
Luo, Yang-Hui
Jiang, Ye-Hao
Sun, Bai-Wang
Source :
Research on Chemical Intermediates; Sep2016, Vol. 42 Issue 9, p6947-6957, 11p
Publication Year :
2016

Abstract

The compound {[Zn(μ-dicyanamide)(pyrazinamide)](pyrazinamide)} has been synthesized and further characterized by elemental analysis, single-crystal X-ray diffraction, and thermogravimetric analysis. Structural analysis revealed that the dicyanamide anion acted as bridging ligand in a μ-1,5 mode, resulting a polymeric 1-D chain structure. The pairwise N3-H3B···N1 and N9-H9B···N7, N3-H3A···O2 and N9-H9A···O1, N3-H3B···N7 and N9-H9B···N1 multiple hydrogen bonding interactions, impart enhanced stability to supramolecular structures. Hirshfeld surfaces and fingerprint plots were applied to arrive at the same conclusion, which is stabilised mainly by H-H, N-H, O-H interactions. DNA binding studies showed that the compound had interacted with DNA. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09226168
Volume :
42
Issue :
9
Database :
Complementary Index
Journal :
Research on Chemical Intermediates
Publication Type :
Academic Journal
Accession number :
117418898
Full Text :
https://doi.org/10.1007/s11164-016-2506-y