Back to Search
Start Over
Synthesis and characterization of biodegradable pHEMA-starch composites for immobilization of L-asparaginase.
- Source :
- Polymer Bulletin; Jul2016, Vol. 73 Issue 7, p1891-1907, 17p
- Publication Year :
- 2016
-
Abstract
- In this paper, poly (2-hydroxyethyl methacrylate) (pHEMA) and poly (2-hydroxyethyl methacrylate)-starch (pHEMA-S) composites were prepared from 2-hydroxyethyl methacrylate and different ratio starch. The pHEMA-S showed high thermal stability and biodegradability. The biodegradability of pHEMA-S composites was in the range of 14-22 % for 4 weeks depending on the starch ratio of pHEMA-S. Then, L-ASNase was immobilized onto pHEMA-S composites. The immobilized L-ASNase was investigated with optimum temperature, pH and kinetic parameters. Immobilization improved the pH stability and thermal stability of the enzyme. The K values were 1.58 and 0.56 mM for free and immobilized enzyme, respectively. [ABSTRACT FROM AUTHOR]
- Subjects :
- ASPARAGINASE
POLYHEMA
HYDROXYETHYL starch
THERMAL stability
AMIDASES
Subjects
Details
- Language :
- English
- ISSN :
- 01700839
- Volume :
- 73
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Polymer Bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 117358345
- Full Text :
- https://doi.org/10.1007/s00289-015-1583-1