Palladium-Catalyzed Cascade Reactions of α-Halo- N-Tosylhydrazones, Indoles, and Aryl Iodides.

α-Halo- N-tosylhydrazones are explored as reagents for the multiple carbon-carbon bond formations in palladium-catalyzed three-component reactions. A strategy has been designed for this transformation by using a nucleophile to react with the azoalkene intermediate formed in situ from the α-halo- N-tosylhydrazone to generate the diazo intermediate, which is further subjected to palladium-catalyzed C−C bond forming reactions with aryl iodides. [ABSTRACT FROM AUTHOR]