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Exocytotic Release of [3H]-Acetylcholine by Ouabain Involves Intracellular Ca2+ Stores in Rat Brain Cortical Slices.

Authors :
Lomeo, Rosangela S.
Gomez, Renato S.
Prado, Marco Antonio M.
Romano-Silva, Marco Aurélio
Massensini, André R.
Gomez, Marcus V.
Source :
Cellular & Molecular Neurobiology; Dec2003, Vol. 23 Issue 6, p917-927, 11p
Publication Year :
2003

Abstract

Investigates the effect of ouabain on the release of [[sup 3]H]acetylcholine ([[sup 3]H]ACh) in rat brain cortical slices. Evidence that the ouabain-induced release of ([[sup 3]H]ACh) was calcium-independent and not blocked by EGTA; Suggestion that ouabain causes Ca[sup 2+] release from intracellular stores that can increase ([[sup 3]H]ACh) exocytosis from rat brain cortical slices.

Details

Language :
English
ISSN :
02724340
Volume :
23
Issue :
6
Database :
Complementary Index
Journal :
Cellular & Molecular Neurobiology
Publication Type :
Academic Journal
Accession number :
11638545