Back to Search Start Over

Cover Picture: Copper-Catalyzed Double Decarboxylative Coupling Reactions of Alkynyl Carboxylic Acid and Glyoxylic Acid: Synthesis of Propargyl Amines and Imidazopyridines (Asian J. Org. Chem. 6/2016).

Authors :
Choi, Jinseop
Lim, Jeongah
Irudayanathan, Francis Mariaraj
Kim, Han ‐ Sung
Park, Jaerim
Yu, Su BeEN
Jang, Yuna
Raja, Gabriel Charles Edwin
Nam, Kye Chun
Kim, Jimin
Lee, Sunwoo
Source :
Asian Journal of Organic Chemistry; Jun2016, Vol. 5 Issue 6, p710-710, 1p
Publication Year :
2016

Abstract

A double decarboxylative coupling reaction was developed. Alkynyl carboxylic acids, glyoxylic acid, and amines were reacted in the presENce of a copper catalyst to afford the corresponding propargyl amines in good yields. It was found that the alkynyl carboxylic acid showed similar reactivity to a terminal alkyne, and the reactivity of glyoxylic acid was almost idENtical to that of an aldehyde in this coupling reaction. More information can be found in the full paper by S. Lee and co ‐ workers on page   770 in Issue 6, 2016 (DOI: 10.1002/ajoc.201600109). [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
21935807
Volume :
5
Issue :
6
Database :
Complementary Index
Journal :
Asian Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
116172198
Full Text :
https://doi.org/10.1002/ajoc.201600236