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bcTol: a highly water-soluble biradical for efficient dynamic nuclear polarization of biomolecules.

Authors :
Jagtap, Anil P.
Geiger, Michel-Andreas
Stöppler, Daniel
Orwick-Rydmark, Marcella
Oschkinat, Hartmut
Sigurdsson, Snorri Th.
Source :
Chemical Communications; 5/28/2016, Vol. 52 Issue 43, p7020-7023, 4p
Publication Year :
2016

Abstract

Dynamic nuclear polarization (DNP) is an efficient method to overcome the inherent low sensitivity of magic-angle spinning (MAS) solid-state NMR. We report a new polarizing agent (bcTol), designed for biological applications, that yielded an enhancement value of 244 in a microcrystalline SH3 domain sample at 110 K. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
52
Issue :
43
Database :
Complementary Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
115471207
Full Text :
https://doi.org/10.1039/c6cc01813k