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Iron-Catalyzed Regioselective Transfer Hydrogenative Couplings of Unactivated Aldehydes with Simple Alkenes.

Authors :
Zheng, Yan‐Long
Liu, Yan‐Yao
Wu, Yi‐Mei
Wang, Yin‐Xia
Lin, Yu‐Tong
Ye, Mengchun
Source :
Angewandte Chemie International Edition; 5/17/2016, Vol. 55 Issue 21, p6315-6318, 4p
Publication Year :
2016

Abstract

An FeBr<subscript>3</subscript>-catalyzed reductive coupling of various aldehydes with alkenes that proceeds through a direct hydride transfer pathway has been developed. With <superscript> i</superscript>PrOH as the hydrogen donor under mild conditions, previously challenging coupling reactions of unactivated alkyl and aryl aldehydes with simple alkenes, such as styrene derivatives and α-olefins, proceeded smoothly to furnish a diverse range of functionalized alcohols with complete linear regioselectivity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14337851
Volume :
55
Issue :
21
Database :
Complementary Index
Journal :
Angewandte Chemie International Edition
Publication Type :
Academic Journal
Accession number :
115295122
Full Text :
https://doi.org/10.1002/anie.201602130