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Social/economic costs and health-related quality of life in patients with histiocytosis in Europe.
- Source :
- European Journal of Health Economics; Apr2016 Supplement, Vol. 17, p67-78, 12p
- Publication Year :
- 2016
-
Abstract
- <bold>Objective: </bold>The aim of this study was to determine the economic burden from a societal perspective and the health-related quality of life (HRQOL) of patients with histiocytosis in Europe.<bold>Methods: </bold>We conducted a cross-sectional study of patients with histiocytosis from France, Germany, Italy, Spain, Bulgaria, the UK, and Sweden. Data on demographic characteristics, health resource utilisation, informal care, loss of labour productivity and HRQOL were collected from the questionnaires completed by patients or their caregivers. HRQOL was measured with the EuroQol 5-domain (EQ-5D) questionnaire.<bold>Results: </bold>A total of 134 patients (35 France, 32 Germany, 30 Italy, 24 Spain, 7 Bulgaria, 4 UK and 2 Sweden) completed the questionnaire. The average annual costs ranged from € 6832 to € 33,283 between countries, the year of reference being 2012. Estimated direct healthcare costs ranged from € 1698 to € 18,213; direct nonhealthcare costs ranged from € 2936 to € 17,622 and labour productivity losses ranged from € 1 to € 8855. The mean EQ-5D score for adult histiocytosis patients was estimated at between 0.32 and 0.85, and the mean EQ-5D visual analogue scale score was estimated at between 50.00 and 66.50.<bold>Conclusion: </bold>The main strengths of this study lie in our bottom-up approach to costing and in the evaluation of histiocytosis patients from a broad perspective (societal costs). This type of analysis is very scarce in international literature for rare diseases in comparison with other illnesses. We conclude that histiocytosis patients incur considerable societal costs and experience substantial deterioration in HRQOL. [ABSTRACT FROM AUTHOR]
- Subjects :
- QUALITY of life
DEMOGRAPHIC characteristics
MEDICAL care use
LABOR productivity
INDUSTRIAL costs
MEDICAL economics
SICK leave
PATIENTS
MEDICAL care cost statistics
CAREGIVERS
COMPARATIVE studies
ECONOMIC aspects of diseases
RESEARCH methodology
MEDICAL cooperation
QUESTIONNAIRES
RESEARCH
HISTIOCYTOSIS
SICKNESS Impact Profile
SOCIOECONOMIC factors
EVALUATION research
CROSS-sectional method
ECONOMICS
Subjects
Details
- Language :
- English
- ISSN :
- 16187598
- Volume :
- 17
- Database :
- Complementary Index
- Journal :
- European Journal of Health Economics
- Publication Type :
- Academic Journal
- Accession number :
- 115247233
- Full Text :
- https://doi.org/10.1007/s10198-016-0790-5