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Re-starting smoking in the postpartum period after receiving a smoking cessation intervention: a systematic review.
- Source :
- Addiction; Jun2016, Vol. 111 Issue 6, p981-990, 10p, 1 Diagram, 3 Charts
- Publication Year :
- 2016
-
Abstract
- Aims In pregnant smoking cessation trial participants, to estimate (1) among women abstinent at the end of pregnancy, the proportion who re-start smoking at time-points afterwards (primary analysis) and (2) among all trial participants, the proportion smoking at the end of pregnancy and at selected time-points during the postpartum period (secondary analysis). Methods Trials identified from two Cochrane reviews plus searches of Medline and EMBASE. Twenty-seven trials were included. The included trials were randomized or quasi-randomized trials of within-pregnancy cessation interventions given to smokers who reported abstinence both at end of pregnancy and at one or more defined time-points after birth. Outcomes were validated biochemically and self-reported continuous abstinence from smoking and 7-day point prevalence abstinence. The primary random-effects meta-analysis used longitudinal data to estimate mean pooled proportions of re-starting smoking; a secondary analysis used cross-sectional data to estimate the mean proportions smoking at different postpartum time-points. Subgroup analyses were performed on biochemically validated abstinence. Results The pooled mean proportion re-starting at 6 months postpartum was 43% [95% confidence interval (CI) = 16-72%, I<superscript>2</superscript> = 96.7%] (11 trials, 571 abstinent women). The pooled mean proportion smoking at the end of pregnancy was 87% (95% CI = 84-90%, I<superscript>2</superscript> = 93.2%) and 94% (95% CI = 92-96%, I<superscript>2</superscript> = 88%) at 6 months postpartum (23 trials, 9262 trial participants). Findings were similar when using biochemically validated abstinence. Conclusions In clinical trials of smoking cessation interventions during pregnancy only 13% are abstinent at term. Of these, 43% re-start by 6 months postpartum. [ABSTRACT FROM AUTHOR]
- Subjects :
- CONFIDENCE intervals
INFORMATION storage & retrieval systems
MEDICAL databases
MEDICAL information storage & retrieval systems
MEDLINE
META-analysis
PUERPERIUM
RESEARCH funding
SELF-evaluation
SMOKING
SMOKING cessation
SYSTEMATIC reviews
DISEASE relapse
SECONDARY analysis
RANDOMIZED controlled trials
TREATMENT effectiveness
CROSS-sectional method
PUBLICATION bias
Subjects
Details
- Language :
- English
- ISSN :
- 09652140
- Volume :
- 111
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Addiction
- Publication Type :
- Academic Journal
- Accession number :
- 115197417
- Full Text :
- https://doi.org/10.1111/add.13309