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A history of childhood trauma is associated with slower improvement rates: Findings from a one-year follow-up study of patients with a first-episode psychosis.
- Source :
- BMC Psychiatry; 5/4/2016, Vol. 16, p1-8, 8p, 4 Charts, 1 Graph
- Publication Year :
- 2016
-
Abstract
- Background: The aim of this study was to investigate whether childhood trauma was associated with more severe clinical features in patients with first-episode psychosis, both at the initial assessment and after one year. Methods: Ninety-six patients with a first-episode of a DSM-IV diagnosis of psychosis, in addition to 264 healthy controls from the same catchment area, were recruited to the TOP NORMENT study. A history of childhood trauma was obtained using the Childhood Trauma Questionnaire (CTQ). Function and symptom severity were measured using the Global Assessment of Functioning (GAF) Scale divided into function (GAF-F) and symptoms (GAF-S), the Positive and Negative Syndrome Scale (PANSS) and the Young Mania Rating Scale (YMRS). All clinical assessments were completed at two time points: At an initial assessment within the first year of initiating treatment for psychosis and after one year. Results: Childhood trauma was associated with significantly reduced global functioning and more severe clinical symptoms at both baseline and follow-up, whereas emotional neglect was associated with a significantly reduced improvement rate for global functioning (GAF-F) over the follow-up period. Conclusion: Our data indicate that patients with first-episode psychosis who report a history of childhood trauma constitute a subgroup characterized by more severe clinical features over the first year of treatment, as well as slower improvement rates. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 1471244X
- Volume :
- 16
- Database :
- Complementary Index
- Journal :
- BMC Psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 115188205
- Full Text :
- https://doi.org/10.1186/s12888-016-0827-4