Back to Search Start Over

Cover Picture: Total Synthesis and Complete Stereostructure of a Marine Macrolide Glycoside, (−)-Lyngbyaloside B (Chem. Eur. J. 20/2016).

Authors :
Fuwa, Haruhiko
Yamagata, Naoya
Okuaki, Yuta
Ogata, Yuya
Saito, Asami
Sasaki, Makoto
Source :
Chemistry - A European Journal; 5/10/2016, Vol. 22 Issue 20, p6697-6697, 1p
Publication Year :
2016

Abstract

Structural reassignment: Total synthesis of the proposed and correct structures of (−) ‐ lyngbyaloside B (see figure), a marine macrolide glycoside, has been achieved. The synthesis entailed an Abiko – Masamune aldol reaction, a vinylogous Mukaiyama aldol reaction, and an acyl ketene macrocyclization to forge the 14 ‐ membered macrolactone. The present work established the complete stereostructure of this natural product in an unambiguous manner. More information can be found in the Full Paper by H. Fuwa et al. on page 6815 ff. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09476539
Volume :
22
Issue :
20
Database :
Complementary Index
Journal :
Chemistry - A European Journal
Publication Type :
Academic Journal
Accession number :
115061952
Full Text :
https://doi.org/10.1002/chem.201601249