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Bioinformatic analysis of c-Myc target from laryngeal cancer cell gene of laryngeal cancer.

Authors :
Wei-Dong Zhang
He-Xin Chen
Yun-Xia Wang
Zhi-Ping Chen
Zhong-Jie Shan
Guang Xu
Zhang, Wei-Dong
Chen, He-Xin
Wang, Yun-Xia
Chen, Zhi-Ping
Shan, Zhong-Jie
Xu, Guang
Source :
Journal of Cancer Research & Therapeutics; Jan-Mar2016, Vol. 12 Issue 1, p58-61, 4p
Publication Year :
2016

Abstract

<bold>Aim Of Study: </bold>The aim was to explore the structure and functions of new target spot c-Myc target from laryngeal cancer cell. (MTLC) of c-Myc gene.<bold>Methods: </bold>This study adopted bioinformatic methods to analyze the physicochemical property, secondary structure, hydrophobic region, a transmembrane region, and prediction of functions.<bold>Results: </bold>The results showed that the whole length of the open reading frames was 708 bp, coding was 235 amino acids. This protein was a basic protein possessed two transmembrane structures and weight was about 26592.5 Da. The main elements of secondary structure were alpha-helix and random coil. MTLC was a membrane constitutive protein that possessed signal transduction and regulation may locate on karyotheca as results of subcellular localization and function prediction.<bold>Conclusion: </bold>This study has provided the theoretical basis for the further discussion of the effect and mechanism of action of MTLC in the occurrence of laryngeal cancer. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09731482
Volume :
12
Issue :
1
Database :
Complementary Index
Journal :
Journal of Cancer Research & Therapeutics
Publication Type :
Academic Journal
Accession number :
114615099
Full Text :
https://doi.org/10.4103/0973-1482.146083