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Affinity-based thermoresponsive precipitation of proteins modified with polymer-binding peptides.
- Source :
- Chemical Communications; 4/28/2016, Vol. 52 Issue 33, p5670-5673, 4p
- Publication Year :
- 2016
-
Abstract
- A 12-mer peptide with an affinity for the meso diad sequence of poly(N-isopropylacrylamide) (PNIPAM) was identified through affinity-based peptide screening. A model protein (i.e., human serum albumin (HSA)) chemically modified with the peptide was successfully precipitated with PNIPAM above the lower critical solution temperature (LCST) of PNIPAM. [ABSTRACT FROM AUTHOR]
- Subjects :
- PEPTIDES
PROTEINS
TEMPERATURE
SERUM albumin
SERUM
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 52
- Issue :
- 33
- Database :
- Complementary Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 114542547
- Full Text :
- https://doi.org/10.1039/c6cc00594b