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Cognitive Reserve, Incident Dementia, and Associated Mortality in the Ibadan Study of Ageing.
- Source :
- Journal of the American Geriatrics Society; Mar2016, Vol. 64 Issue 3, p590-595, 6p, 3 Charts
- Publication Year :
- 2016
-
Abstract
- Objectives To describe factors associated with incident dementia and dementia mortality over 5 years in a large community sample of elderly persons. Design Longitudinal investigation of a household multistage probability sample. Setting Eight contiguous states of the Yoruba-speaking region of Nigeria. Participants Individuals aged 65 and older (N = 2,149). Measurements Dementia was diagnosed using tools previously validated in the population. Incident cases of dementia over three follow-up waves were determined after censoring cases in the preceding wave. Information on mortality was collected from key informants in subjects' households. Results A dementia incident rate was found of 20.9 per 1,000 person-years (95% confidence interval ( CI) = 17.7-24.9). The adjusted mortality hazard for those with dementia was 1.5 (95% CI = 1.1-2.1). Along with previously identified social and demographic factors, poor predementia cognitive function (hazard ratio ( HR) = 1.8, 95% CI = 1.1-2.8) and low occupational complexity ( HR = 3.2, 95% CI = 1.3-8.0) were associated with incident dementia. Conclusion The findings confirm the low incidence of dementia in this population, as previously reported. The condition is nevertheless associated with higher risk of mortality. Along with some features of social disadvantage, proxies of lower cognitive reserve were risk factors for incident dementia. [ABSTRACT FROM AUTHOR]
- Subjects :
- DEMENTIA research
MORTALITY
AGING
EPIDEMIOLOGY
LOW-income countries
SOCIAL disabilities
DIAGNOSIS of dementia
DEMENTIA risk factors
GERIATRIC assessment
BODY weight
CHI-squared test
CHRONIC diseases
COGNITION in old age
CONFIDENCE intervals
DEMENTIA
MENTAL depression
ALCOHOL drinking
INTERVIEWING
LIFE skills
LONGITUDINAL method
RESEARCH methodology
PROBABILITY theory
PSYCHOLOGICAL tests
QUESTIONNAIRES
REGRESSION analysis
RESEARCH funding
STATISTICAL sampling
SCALE analysis (Psychology)
SMOKING
SOCIAL participation
SURVEYS
ACTIVITIES of daily living
PSYCHOSOCIAL factors
SOCIOECONOMIC factors
DATA analysis software
DESCRIPTIVE statistics
KAPLAN-Meier estimator
CLUSTER sampling
OLD age
Subjects
Details
- Language :
- English
- ISSN :
- 00028614
- Volume :
- 64
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Journal of the American Geriatrics Society
- Publication Type :
- Academic Journal
- Accession number :
- 113900385
- Full Text :
- https://doi.org/10.1111/jgs.14015