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Effect of a high-fat meal containing conventional or high-oleic peanuts on post-prandial lipopolysaccharide concentrations in overweight/obese men.
- Source :
- Journal of Human Nutrition & Dietetics; Feb2016, Vol. 29 Issue 1, p95-104, 10p, 3 Charts, 3 Graphs
- Publication Year :
- 2016
-
Abstract
- Background An increased plasma lipopolysaccharide ( LPS) concentration may favour metabolic disorders such as insulin resistance. The meal composition influences plasma LPS concentrations. The present study aimed to investigate the effect of the acute consumption of a high-fat meal (49% of energy from fat) containing conventional or high-oleic peanuts on post-prandial LPS concentrations and its relationship with lipaemia and insulinaemia in overweight and obese men. Methods The test meal consisted of a shake containing conventional peanuts ( CVP; n = 21), high-oleic peanuts ( HOP; n = 23) or a control biscuit ( CT; n = 21). Blood samples were collected in the fasting state and 1, 2 and 3 h post-prandially. LPS, insulin, lipids and glucose concentrations were assessed. Results LPS concentrations were lower in CVP [mean (SE) 0.7 (0.5) EU mL<superscript>−1</superscript>] and HOP [1.0 (0.9) EU mL<superscript>−1</superscript>] groups compared to CT [1.6 (1.2) EU mL<superscript>−1</superscript>] at 3 h post-prandially. Triacylglycerol and insulin concentrations increased in all groups. Triacylglycerol started to increase only after 2 h in the CVP and HOP groups. LPS correlated positively with triacylglycerol. Insulin returned to basal concentrations at 3 h only in the CVP and HOP groups. Conclusions The acute consumption of peanuts delayed the increase in serum triacylglycerol and favoured the quicker return of insulin to basal concentrations, especially in the CVP group. Our results suggest that the consumption of conventional or high-oleic peanuts may help to reduce the risk of endotoxaemia and metabolic disorders. [ABSTRACT FROM AUTHOR]
- Subjects :
- BLOOD sugar analysis
BODY composition
ANALYSIS of covariance
ANALYSIS of variance
ANTHROPOMETRY
BEVERAGES
CHOLESTEROL
CLINICAL trials
CONFIDENCE intervals
FAT content of food
BIOELECTRIC impedance
INGESTION
INSULIN
MEN'S health
OBESITY
PEANUTS
RESEARCH funding
STATISTICAL sampling
STATISTICS
TIME
TRIGLYCERIDES
UNSATURATED fatty acids
STATISTICAL power analysis
DATA analysis
BODY mass index
RANDOMIZED controlled trials
REPEATED measures design
DATA analysis software
LIPOPOLYSACCHARIDES
DESCRIPTIVE statistics
KRUSKAL-Wallis Test
Subjects
Details
- Language :
- English
- ISSN :
- 09523871
- Volume :
- 29
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Journal of Human Nutrition & Dietetics
- Publication Type :
- Academic Journal
- Accession number :
- 112507405
- Full Text :
- https://doi.org/10.1111/jhn.12284