Study of the inclusion complex and antioxidating activity of Wogonin with β-cyclodextrin and hydroxypropyl-cyclodextrin.

The aim of the study was to synthesize the complexes of Wogonin with β-cyclodextrin (β-CD) and hydroxypropyl-cyclodextrin (HP-β-CD) by refluxing method, and the experimental resulted confirmed the forming of Wogonin complexes with CDs by nuclear magnetic resonance spectroscopy, infrared spectra and differential scanning calorimetry at 60 °C refluxing for 6 h. Kinetic studies of 2,2-diphenyl-1-picrylhydrazyl (DPPH·) with Wogonin and cyclodextrins (CDs) complexes were done. The results obtained indicated that the Wogonin/HP-β-CD complex was the most reactive form. [ABSTRACT FROM AUTHOR]