Back to Search
Start Over
Randomized Controlled Trial of Hospital-Based Hygiene and Water Treatment Intervention (CHoBI7) to Reduce Cholera.
- Source :
- Emerging Infectious Diseases; Feb2016, Vol. 22 Issue 2, p233-241, 9p, 1 Color Photograph, 1 Diagram, 4 Charts
- Publication Year :
- 2016
-
Abstract
- The risk for cholera infection is >100 times higher for household contacts of cholera patients during the week after the index patient seeks hospital care than it is for the general population. To initiate a standard of care for this high-risk population, we developed Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7), which promotes hand washing with soap and treatment of water. To test CHoBI7, we conducted a randomized controlled trial among 219 intervention household contacts of 82 cholera patients and 220 control contacts of 83 cholera patients in Dhaka, Bangladesh, during 2013-2014. Intervention contacts had significantly fewer symptomatic Vibrio cholerae infections than did control contacts and 47% fewer overall V. cholerae infections. Intervention households had no stored drinking water with V. cholerae and 14 times higher odds of hand washing with soap at key events during structured observation on surveillance days 5, 6, or 7. CHoBI7 presents a promising approach for controlling cholera among highly susceptible household contacts of cholera patients. [ABSTRACT FROM AUTHOR]
- Subjects :
- PREVENTION of cholera
WATER disinfection
HAND washing
COMMUNICABLE diseases
PUBLIC health
CROSS infection prevention
CHOLERA
COMPARATIVE studies
CROSS infection
FAMILIES
GRAM-negative bacteria
HOSPITALS
HYGIENE
RESEARCH methodology
MEDICAL cooperation
RESEARCH
RESEARCH funding
WATER supply
EVALUATION research
RANDOMIZED controlled trials
ODDS ratio
Subjects
Details
- Language :
- English
- ISSN :
- 10806040
- Volume :
- 22
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Emerging Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 112410843
- Full Text :
- https://doi.org/10.3201/eid2202.151175