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Organocatalysis by an aprotic imidazolium zwitterion: regioselective ring-opening of aziridines and applicable to gram scale synthesis.
- Source :
- Green Chemistry; 1/21/2016, Vol. 18 Issue 2, p565-574, 10p
- Publication Year :
- 2016
-
Abstract
- An imidazole-based zwitterionic-salt, 4-(3-methylimidazolium)butane sulfonate (MBS), has been found to be an efficient organocatalyst for aziridine ring-opening regioselectively by various nucleophiles like indoles, pyrroles, methanol, ethanol, acetic acid and di-iso-propylamine. The reactions are highly regioselective and they always afford the products resulting from benzylic attack. The present methodology is applicable to gram scale synthesis. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14639262
- Volume :
- 18
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Green Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 112344826
- Full Text :
- https://doi.org/10.1039/c5gc01323b