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missMethyl: an R package for analyzing data from Illumina's HumanMethylation450 platform.
- Source :
- Bioinformatics; 1/15/2016, Vol. 32 Issue 2, p286-288, 3p
- Publication Year :
- 2016
-
Abstract
- DNA methylation is one of the most commonly studied epigenetic modifications due to its role in both disease and development. The Illumina HumanMethylation450 BeadChip is a costeffective way to profile >450 000 CpGs across the human genome, making it a popular platform for profiling DNA methylation. Here we introduce missMethyl, an R package with a suite of tools for performing normalization, removal of unwanted variation in differential methylation analysis, differential variability testing and gene set analysis for the 450K array. [ABSTRACT FROM AUTHOR]
- Subjects :
- METHYL groups
METHYLATION
DATA analysis
HUMAN genome
COST effectiveness
Subjects
Details
- Language :
- English
- ISSN :
- 13674803
- Volume :
- 32
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Bioinformatics
- Publication Type :
- Academic Journal
- Accession number :
- 112207515
- Full Text :
- https://doi.org/10.1093/bioinformatics/btv560