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Pedunculopontine Gamma Band Activity and Development.

Authors :
Garcia-Rill, Edgar
Luster, Brennon
Mahaffey, Susan
MacNicol, Melanie
Hyde, James R.
D'Onofrio, Stasia M.
Phillips, Cristy
Source :
Brain Sciences (2076-3425); 2015, Vol. 5 Issue 4, p546-567, 22p
Publication Year :
2015

Abstract

This review highlights the most important discovery in the reticular activating system in the last 10 years, the manifestation of gamma band activity in cells of the reticular activating system (RAS), especially in the pedunculopontine nucleus, which is in charge of waking and rapid eye movement (REM) sleep. The identification of different cell groups manifesting P/Q-type Ca<superscript>2+</superscript> channels that control waking vs. those that manifest N-type channels that control REM sleep provides novel avenues for the differential control of waking vs. REM sleep. Recent discoveries on the development of this system can help explain the developmental decrease in REM sleep and the basic rest-activity cycle. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
RAPID eye movement sleep
HEALTH

Details

Language :
English
ISSN :
20763425
Volume :
5
Issue :
4
Database :
Complementary Index
Journal :
Brain Sciences (2076-3425)
Publication Type :
Academic Journal
Accession number :
111972240
Full Text :
https://doi.org/10.3390/brainsci5040546