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Ultrasonic assessment of the effects of self-assembling peptide scaffolds on preventing enamel demineralization.
- Source :
- Acta Odontologica Scandinavica; Mar2016, Vol. 74 Issue 2, p142-147, 6p
- Publication Year :
- 2016
-
Abstract
- <bold>Objectives: </bold>This study evaluates the effect of self-assembling peptide P11-4 (Curodont Repair, CDR) on bovine enamel remineralization by measuring changes in ultrasonic propagation velocity.<bold>Methods: </bold>Six specimens per group were prepared by sectioning bovine teeth into enamel blocks. These blocks were then immersed in lactic acid buffer solution (pH = 4.75) for 10 min twice a day and stored in artificial saliva. Other specimens were first treated with CDR, followed by a 10-min immersion in the lactic acid buffer solution twice a day, before storage in artificial saliva. The propagation time of longitudinal ultrasonic waves was measured using a pulser/receiver. Six specimens were used for each treatment protocol. The obtained data were statistically analyzed using ANOVA followed by Tukey's honestly significant difference tests (α = 0.05). Specimens were observed using laser scanning microscopy and scanning electron microscopy.<bold>Results: </bold>Sonic velocity was found to decrease with time for specimens stored in the demineralizing solution. On the other hand, increases in sonic velocity were found for specimens treated with CDR. These specimens also exhibited signs of mineral deposition.<bold>Conclusions: </bold>By measuring the ultrasonic propagation velocity, it can be concluded that CDR application has an ability to promote bovine enamel remineralization. [ABSTRACT FROM AUTHOR]
- Subjects :
- ULTRASONIC imaging
MOLECULAR self-assembly
PEPTIDES
TOOTH demineralization
DENTAL enamel
OLIGOPEPTIDES
ANIMAL experimentation
BUFFER solutions
CATTLE
COMPARATIVE studies
HYDROGEN-ion concentration
LACTIC acid
RESEARCH methodology
MEDICAL cooperation
MICROSCOPY
MINERALS
RESEARCH
SCANNING electron microscopy
EVALUATION research
REMINERALIZATION (Teeth)
ARTIFICIAL saliva
PREVENTION
THERAPEUTICS
Subjects
Details
- Language :
- English
- ISSN :
- 00016357
- Volume :
- 74
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Acta Odontologica Scandinavica
- Publication Type :
- Academic Journal
- Accession number :
- 111889647
- Full Text :
- https://doi.org/10.3109/00016357.2015.1066850