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Synthesis and Antifungal Activity Against Candida Albicans of 6-Aryl-3,4-Dimethyl- N-Phenyl-2-Oxo-1,2,3,6-Tetrahydropyrimidine-5-Carboxamides.
- Source :
- Pharmaceutical Chemistry Journal; Nov2015, Vol. 49 Issue 8, p509-511, 3p
- Publication Year :
- 2015
-
Abstract
- 6-Aryl-3,4-dimethyl- N-phenyl-2-oxo-1,2,3,6-tetrahydropyrimidine-5-carboxamides were synthesized by three-component reactions of acetoacetanilide, aromatic aldehydes, and N-methylurea. The structures of the compounds were confirmed by IR and PMR spectroscopy and mass spectrometry. The antifungal activity of the synthesized compounds was studied. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0091150X
- Volume :
- 49
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Pharmaceutical Chemistry Journal
- Publication Type :
- Academic Journal
- Accession number :
- 111160485
- Full Text :
- https://doi.org/10.1007/s11094-015-1316-7