Electrochemical Treatment of Glassy Carbon for Label-Free Detection of DNABases and Neurotransmitters.

Electrochemically reduced glassy carbon (r-GC) showed a superior electrochemical sensing performance, compared to oxidized GC (ox-GC) and untreated GC for the oxidation of 4DNA bases and neurotransmitters (epinephrine, norepinephrine and serotonin). r-GC exhibited not only the largest current intensities of all redox biomolecules, but also displayed an excellent selectivity in detecting coexisting redox biomolecules. The enhanced performance of r-GC was attributed to the improved surface cleanliness of electrode and its catalytic surface functional groups. The results presented herein imply that simple electrochemical treatments are aviable method to produce sensitive and selective electrodes for label-free biosensing. [ABSTRACT FROM AUTHOR]