The use of a collagen matrix in hard-to-heal venous leg ulcers.

Objective: The effects of a collagen dressing on hard-to-heal venous leg ulcers (VLUs) were evaluated in this prospective, randomised, controlled study. Method: Patients with hard-to-heal VLU were included and divided into two groups using the block randomisation method. The first group was treated with a collagen and an alginate dressing (group A), and the second group with an alginate dressing alone (group b). both groups also had a short-stretch compression system applied at every dressing change. The dressings were changed twice a week for 12 weeks or until the ulcer was healed. Granulation tissue improvement, wound size, overall dressing performance and dressing comfort were evaluated and recorded. Results: A total of 40 patients completed the study evaluation period. Group A had a 65% increase in granulation tissue compared to 38% in group b. The mean ulcer area was reduced to 45% in group A compared to 20% in group b at 12 weeks. no significant side effects were detected in either group. Patients of both groups were satisfied with their treatment and healing progress. Conclusion: The results of this study showed the effectiveness and safety of a collagen dressing in hard-to-heal VLUs as an adjunctive therapy with compression bandaging. These encouraging results may positively affect the quality of life of patients with chronic wounds. Declaration of interest: The research was funded with an unrestricted grant from medSkin Solutions. [ABSTRACT FROM AUTHOR]