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The predictive role of infiltrative growth pattern in early pharyngeal cancers.
- Source :
- Acta Oto-Laryngologica; Nov2015, Vol. 135 Issue 11, p1172-1177, 6p
- Publication Year :
- 2015
-
Abstract
- Conclusion: The infiltrative growth pattern may predict tumor depth and lymph node metastasis. INF-a seems to fall into a low-risk category, and no additional treatment may be required immediately. Objectives: Tumor depth is a predictor of lymph node metastasis in early pharyngeal cancers. An infiltrative growth pattern is also a prognostic factor in other cancers. This study aimed to elucidate the predictive role of infiltrative growth pattern in early pharyngeal cancers. Methods: Thirty-eight lesions from 37 patients who had undergone trans-oral resection of pharyngeal cancers were included. According to the Japanese Classification of Esophageal Cancer, infiltrative growth pattern was classified into three groups; INF-a, INF-b, and INF-c. The correlation between infiltrative growth pattern and tumor depth, cervical lymph node metastasis was analyzed. Results: Of the 38 lesions, 25 were INF-a, nine were INF-b, and four were INF-c lesions. Lymph node metastasis was observed in three INF-b and one INF-c lesions. In contrast, no INF-a had lymph node metastasis. All INF-a lesions showed shallow invasion of the sub-epithelium; INF-b and INF-c lesions had significantly greater depth than INF-a. [ABSTRACT FROM AUTHOR]
- Subjects :
- CELL analysis
ACADEMIC medical centers
ANALYTICAL biochemistry
COLLECTION & preservation of biological specimens
CANCER invasiveness
CHI-squared test
HISTOLOGICAL techniques
LYMPH nodes
METASTASIS
PHARYNX tumors
PROBABILITY theory
STATISTICS
TUMOR classification
DATA analysis
RETROSPECTIVE studies
DATA analysis software
DESCRIPTIVE statistics
MANN Whitney U Test
KRUSKAL-Wallis Test
Subjects
Details
- Language :
- English
- ISSN :
- 00016489
- Volume :
- 135
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- Acta Oto-Laryngologica
- Publication Type :
- Academic Journal
- Accession number :
- 109966973
- Full Text :
- https://doi.org/10.3109/00016489.2015.1072872